After completing the apprenticeship as a mechanic, Simon Wüest studied Systems Engineering (bachelor) at the University of Applied Sciences Northwestern Switzerland. Subsequently he studied Biomedical Engineering (master) at the University of Bern. As a part-time student he also worked as an assistant at the University of Applied Sciences Northwestern Switzerland. He developed so-called Random Positioning Machines (RPM), which are used to expose biological samples to simulated microgravity. Currently he is doing his PhD in Biomedical Engineering in a collaborative work of the Lucerne University of Applied Sciences and Arts and the University of Bern. He is studying the effect of microgravity on cartilage and the possible role of mechanosensitive ion channels.