Giger Christina HSLU T&A

Dr. Christina Giger Christina Giger - Lange

Senior Research Associate

Giger Christina HSLU T&A

Lucerne School of Engineering and Architecture

Room 360
Obermattweg 9
6052 Hergiswil NW


Institute of Medical Engineering IMT

CC Bioscience and Medical Engineering

Senior Research Associate

+41 41 349 36 68

Show email

Biography

Ausbildung:

University of Zurich, Retinal Cell Biology, PhD, 2007-2010

ETH Zurich, Biology, Neuroscience, Master of Science, 2001-2006

Berufliche Tätigkeiten:

2019-heute: Senior wissenschaftliche Mitarbeiterin am Institut für Medizintechnik (IMT), Forschungsgruppe Biomedical engineering

  • Leitung des Oertli Research Lab: Auftragsforschung im Bereich Ophthalmologie für die Firma Oertli Instrumente AG
  • Leitung des mikrobiologischen Analyselabors in Zusammenarbeit mit der Forschungsgruppe Gesundheit und Hygiene des IGE
  • Forschungstätigkeit in verschiedenen Innosuisse und anderen Forschungsprojekten im Bereich Medizintechnik und Weltraumforschung
  • Lehrtätigkeit in den Modulen Laborkurs, Zellbiologie, Chemie und Anatomie/Physiologie

2016-2019: Wissenschaftliche Mitarbeiterin am Institut für Medizintechnik (IMT), Forschungsgruppe Biomedical engineering

2012-2016: Wissenschaftliche Koordinatorin am Zurich Center for Integrative Human Physiology (ZIHP), Universität Zürich

PUBLICATIONS:

Scientific articles: 9 scientific articles published in peer reviewed journals (neuroscience, ophthalmology, current biology).

Selected publications:

Lange C, Heynen SR, Tanimoto N, Thiersch M, Le YZ, Meneau I, Seeliger MW, Samardzija M, Caprara C, Grimm C. Normoxic activation of hypoxia-inducible factors in photoreceptors provides transient protection against light-induced retinal degeneration. Invest Ophthalmol Vis Sci. 2011 Jul 29;52(8):5872-80.

Lange C, Caprara C, Tanimoto N, Beck S, Huber G, Samardzija M, Seeliger M, Grimm C. Retina-specific activation of a sustained hypoxia-like response leads to severe retinal degeneration and loss of vision. Neurobiol Dis. 2011 Jan;41(1):119-30.

Lange C, Thiersch M, Samardzija M, Bürgi S, Joly S, Grimm C. LIF-dependent JAK3 activation is not essential for retinal degeneration. J Neurochem. 2010 Jun;113(5):1210-20.

Lange C, Thiersch M, Samardzija M, Grimm C. The differential role of Jak/STAT signaling in retinal degeneration. Adv Exp Med Biol. 2010;664:601-7.

Book chapters:

1 book chapter published in “Retinal Degenerative Diseases”, Springer Wien New York.

Press articles:

8 press articles published in “lifesciencesPlus” and on “UZH News”.

 

 

Projects

Research projects

  • Space Bioreactor
  • Sichere und effiziente Glaskörperentfernung bei Netzhautoperationen
  • IGE Innovationswettbewerb 2024
  • Green Health Care Buildings
  • Standard for Space Bioreactors
  • OoDrop
  • Safe and efficient removal of the cataractous lens during cataract surgery
  • Reparatur und Regeneration der Bandscheibe
  • CaSiPaC - Calcium Signaling during Parabolic Flight in Chondrocytes
  • Plant Physiology under Microgravity
  • COW – Cartilage ExpOsed to Weightlessness
  • SpaceFab - an algal biomodule for a nanosatellite
  • Swiss Parabolic Flight 2016

Publications and presentations

Publications and presentations - Article, review; peer reviewed

  • Rattenbacher-Kiser, Karin; Di Lanzo, Jessica; Di Nardo, Silvio; Menapace, Rupert; Ille, Fabian & Giger, Christina (2023). Systematic and objective wet lab testing of instruments for phacoemulsification: New Formalin-Quadrant-Model. Journal of Cataract and Refractive Surgery, doi: 10.1097/j.jcrs.0000000000001322
  • Wüest, Simon; Arnold, Jaro; Gander, Sarah; Zumbühl, Christoph; Jost, Christian; Giger, Christina; Cerretti, Geraldine; Caliò, Martina; Rattenbacher-Kiser, Karin; Follonier, Cindy; Schälli, Othmar; Székely, Gerhard Stefan; Egli, Marcel & Ille, Fabian (2020). Microtubules and Vimentin Fiber Stability during Parabolic Flights. Microgravity Science and Technology, 2020, 1. doi: https://doi.org/10.1007/s12217-020-09818-8
  • Castiglioni, Sara; Cazzaniga, Alessandra; Egli, Marcel; Giger, Christina; Haack, Carsten; Ille, Fabian; Koller, Adrian; Maier, Jeanette; Wüest, Simon & Zocchi, Monika (2020). Scalable Microgravity Simulator Used for Long-Term Musculoskeletal Cells and Tissue Engineering. Molecular Science, Volume 21, Issue 23(Special Issue "Molecular Mechanobiology in Space and on Earth), 44.
  • Wüest, Simon; Caliò, Martina; Wernas, Timon; Tanner, Samuel; Giger, Christina; Wyss, Fabienne; Ille, Fabian; Gantenbein, Benjamin & Egli, Marcel (2018). Influence of Mechanical Unloading on Articular Chondrocyte Dedifferentiation. Ing.J.Mol.Sci., 19(5), 1-18.
  • Egger, Anna; Samardzija, Marijana; Sothilingam, Vithiyanjali; Tanimoto, Naoyuki; Lange, Christina; Salatino, Silvia; Fang, Lei; Garcia-Garrido, Marina; Beck, Susanne; Okoniewski, Michal J.; Neutzer, Albert; Seeliger, Matthias; Grimm, Christian & Handschin, Christoph (2012). PGC-1α determines light damage susceptibility of the murine retina. PLoS ONE, 7(2), 1-12. doi: 10.1371/journal.pone.0031272
  • Giger, Christina; Beck, Susanne; Caprara, Christian; Grimm, Christian; Huber, Gesine; Samardzija, Marijana; Seeliger, Matthias & Tanimoto, Naoyuki (2011). Retina-specific activation of a sustained hypoxia-like response leads to severe retinal degeneration and loss of vision. Neurobiol Dis, 119-130. doi: 10.1016/j.nbd.2010.08.028
  • Giger, Christina; Caprara, Christian; Grimm, Christian; Heynen, Severin; Le, YZ; Meneau, Isabelle; Samardzija, Marijana; Seeliger, Matthias; Tanimoto, Naoyuki & Thiersch, Markus (2011). Normoxic activation of hypoxia-inducible factors in photoreceptors provides transient protection against light-induced retinal degeneration. Invest Ophthalmol Vis Sci., 5872-5880. doi: 10.1167/iovs.11-7204
  • Giger, Christina; Caprara, Christian; Grimm, Christian; Joly, Sandrine; Samardzija, Marijana & Thiersch, Markus (2011). HIF1A is essential for the development of the intermediate plexus of the retinal vasculature. Invest Ophthalmol Vis Sci, 2109-2117. doi: 10.1167/iovs.10-6222
  • Giger, Christina; Bürgi, Sandra; Grimm, Christian; Joly, Sandrine; Samardzija, Marijana & Thiersch, Markus (01.06.2010). LIF-dependent JAK3 activation is not essential for retinal degeneration. Journal of Neurochemistry, 1210-20.
  • Giger, Christina; Grimm, Christian; Heynen, Severin; Joly, Sandrine; Le, Yun Zheng; Samardzija, Marijana & Thiersch, Markus (08.06.2009). Retinal neuroprotection by hypoxic preconditioning is independent of hypoxia-inducible factor-1α expression in photoreceptors. European journal of neuroscience, 2291–2302. doi: 10.1111/j.1460-9568.2009.06781.x
  • Giger, Christina; Grimm, Christian; Joly, Sandrine; Samardzija, Marijana & Thiersch, Markus (17.12.2008). Leukemia Inhibitory Factor Extends the Lifespan of Injured Photoreceptors In Vivo. Neurobiology of Disease, 13765–13774.

Publications and presentations - Chapter/legal commentary/lexicon article

  • Giger, Christina; Grimm, Christian; Samardzija, Marijana & Thiersch, Markus (2009). The differential role of Jak/STAT signaling in retinal degeneration. In Robert E. AndersonJoe G. HollyfieldMatthew M. LaVail (Hrsg.), Adv Exp Med Biol (S. 601-607). New York: Springer.