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  • In vitro investigation of subcutaneous injection distribution
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  1. Lucerne School of Engineering and Architecture Lucerne School of Engineering and Architecture
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  6. In vitro investigation of subcutaneous injection distribution In vitro investigation of subcutaneous injection distribution

In vitro investigation of subcutaneous injection distribution Industry project

Subkutane Injektion

What is it about?

  • Investigating how subcutaneously injected drug formulations distribute in tissue and which factors influence this distribution.
  • This is intended to support data-driven design decisions, reproducible product performance, and regulatory robustness.
     

Projekt objective: 

The aim of the project is the systematic identification, evaluation, and exemplary testing of suitable in vitro methods for reliably visualizing and quantifying fluid distribution after subcutaneous injection in tissue-mimetic models under realistic laboratory conditions. 

In this thesis:

  • you will develop and test tissue-mimetic models (e.g., hydrogels) for simulating subcutaneous tissue structures
  • you will investigate the distribution of model formulations after injection into artificial tissue
  • you will develop methods for visualizing and quantifying fluid distribution
  • combine laboratory work with digital image analysis and data evaluation
     

Possible Master-Profiles:

  • Medical Engineering

 

Prof. Dr. Michael Bufler

Professor

+41 41 349 35 96

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