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  • Protein-based soft tissue replacement
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  1. Lucerne School of Engineering and Architecture Lucerne School of Engineering and Architecture
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  6. Protein-based soft tissue replacement Protein-based soft tissue replacement

Protein-based soft tissue replacement Biomaterials/Regenerative Medicine

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What is it about?

As part of a larger research project, a biointegrative, protein-based matrix for the regeneration of soft tissue (e.g., mucosa) is being developed.
This master's project aims for the theoretical and laboratory-based foundation for targeted product development.

 

 

 

Project objective:

Autologous soft tissue grafts are traditionally considered as clinical gold standard. However, their removal is associated with considerable morbidity, pain for the patient and limitations in the amount that can be harvested. The aim of this interdisciplinary project is to develop an advanced bio-integrative, dimensionally stable and elastic protein-based soft tissue replacement as a patient-friendly alternative.

In this thesis:

  • Develop concepts for an innovative biomaterial for soft tissue regeneration.
  • Work experimentally on the production and characterization of initial biomaterial prototypes.
  • Combine literature analysis with practical laboratory work and modern data evaluation.
  • Gain insights into the early development of a medical device—from material design to biological testing.
  • Work on a product solution that could avoid painful tissue harvesting from patients in the future
     

Possible Master-Profiles:

  • Medical Engineering

Prof. Dr. Michael Bufler

Professor

+41 41 349 35 96

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Lucerne School of Engineering and Architecture


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