Bufler Michael HSLU T&A

Prof. Dr. Michael Bufler Michael Bufler

Professor

Bufler Michael HSLU T&A

Lucerne School of Engineering and Architecture

Room 134
Technikumstrasse 21
6048 Horw


Institute of Medical Engineering IMT

CC Bioscience and Medical Engineering

Professor

+41 41 349 35 96

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Biography

  • 2024- ... Professor and Lecturer for Medical Engineering & Life Science, Hochschule Luzern (HSLU): 

  • 2021-2024: Director of Research, Geistlich Pharma AG

  • 2013-2021: Director of Material Research & Technologies, Geistlich Pharma AG

  • 2008-2012: Associate Director of Core Technologies, Geistlich Pharma AG

  • 2004-2008: Head of Analytical Research, Geistlich Pharma AG

Education

  • Dipl. Min., 
    Johannes-Gutenberg University Mainz, Germany

  • Dr. rer. nat. Chemistry, 
    University of Siegen, Germany. 
    Thesis: «Calciumphosphate - Synthese, Reaktionen in wässrigen Medien und Charakterisierung von Oberflächen und Grenzflächen» 

Associations & Organizations

  • SWISSMEM Industriesektor "Medical Manufacturing" - Member of the executive Committee (https://www.swissmem.ch/de/medical-manufacturing.html)

  • GDCh, German Chemical Society, Member since 1999, Section Member "Solid State Chemistry", "Medicinal Chemistry", "Biochemistry"

Further Training

Preparing for & Surviving an FDA Inspection, CAPA Training, Risikoanalyse und Risikomanagement für Medizinprodukte, Erfolgreiches Projektmanagement in der Praxis, Agiles Projektmanagement (Scrummaster, Product Owner), Gerätequalifizierung und -Überwachung im Analytik Labor, GMP-/FDA Compliance in der Qualitätskontrolle, Particles and Thin Films,  Microencapsulation and Particle Coating, Röntgenbeugung und Rietveldanalyse.

Subjects
  • (1) Grundlagen Physikalische & Analytische Chemie
  • (2) Einführung Laboranalytik
  • (3) Komponenten und Festigkeit von Medizinprodukten
  • (4) Labor- und Personalmanagement
  • (5) Biologische Sicherheit von Medizinprodukten
Professional competencies
  • - Medical Engineering, Medical Devices, Pharma
  • - Research & Product Development from Idea to Product Registration and Beyond
  • - KMU/SME Requirements, Stakeholder Management
  • - Evaluation and Implementation of Customer Needs, Market Requirements and Trends
  • - Product Strategy & Innovation Management
  • - Patenting of Ideas and Concepts (IP) - 165 Globally Registered and Approved Patents
  • - Budget Management, Financial Midterm- and Strategic Longterm Planning
  • International and Interdisciplinary Project Management
  • - Organizational Change Management
  • - Medical Manufacturing related Validation, Qualification and GMP
Teaching and research focus
  • - Materials for Medical Engineering & Life Science
  • - Biomedical Materials Science
  • - Material Selection for Medical Device Products and Medical Manufacturing
  • - Surface- and Interface Science of Biomaterials and Medical Devices
  • - Biomimetic Materials
  • - Advanced Approaches for Bone and Soft Tissue Regeneration
  • - Structure-Property Relationships and Interaction Principles
  • - Hollistic Periimplantitis Approach
  • - Analytical Testing and Material Characterization
  • - Lab-Based Diagnostics
  • - Laboratory Management (GMP / non-GMP)
  • - Biological Safety of Materials and Components

Biomedical Materials Science

- Medical Devices
- Material Science
- Biomaterials
- Material Selection for Medical Manufacturing and Medical Device Products
- Tissue Regeneration
- Bioactive Materials
- Scaffolding in Tissue Engineering

Projects

Research projects

  • IDN - PFAS in der Medizintechnik
  • Detailkonzeptes für eine Zentralschweizer Plattform Kreislaufwirtschaft

Publications and presentations

    • Lindhe, Jan; Araujo, Mauricio; Bufler, Michael & Liljenberg, Birgitta (03.09.2013). Biphasic alloplastic graft used to preserve the dimension of the edentulous ridge: An experimental study in the dog. Clinical Oral Implants Research, 2013(10), 1158-1163.

    • Bufler, Michael (2004). Calciumphosphate : Synthese, Reaktionen in wässrigen Medien und Charakterisierung von Oberflächen und Grenzflächen. Dissertation, Universität Siegen, Deutschland.

Publications and presentations - Article, review; peer reviewed

  • Lindhe, Jan; Araujo, Mauricio; Bufler, Michael & Liljenberg, Birgitta (03.09.2013). Biphasic alloplastic graft used to preserve the dimension of the edentulous ridge: An experimental study in the dog. Clinical Oral Implants Research, 2013(10), 1158-1163.

Publications and presentations - Theses (Bachelor/Master/Dissertation/Habilitation)

  • Bufler, Michael (2004). Calciumphosphate : Synthese, Reaktionen in wässrigen Medien und Charakterisierung von Oberflächen und Grenzflächen. Dissertation, Universität Siegen, Deutschland.

Achievements

    • Bufler, Michael (30.06.2025). Bone substitute material No. 9066995. USA: USPTO.

    • Bufler, Michael (02.05.2023). COLLAGEN MATRIX OR GRANULATE BLEND OF BONE SUBSTITUTE MATERIAL No. ZL202080041436.9. China: CNIPA.

    • Bufler, Michael (23.03.2023). BONE SUBSTITUTE MATERIAL No. 7249376. Japan: JPO.

    • Bufler, Michael (28.12.2022). COLLAGEN MATRIX OR GRANULATE BLEND OF BONE SUBSTITUTE MATERIAL No. 3946488. DE, CH, ES, FR, GB, IT, NL: EPO.

    • Bufler, Michael (16.06.2022). COLLAGEN MATRIX OR GRANULATE BLEND OF BONE SUBSTITUTE MATERIAL No. 11357891. USA: USPTO.

    • Bufler, Michael (07.06.2022). BONE SUBSTITUTE MATERIAL No. 11351287. USA: USPTO.

    • Bufler, Michael (27.01.2022). Method for treating subjects suffering from chronic ulcers No. 20220023498. All Europen countries covered by the EPO, USA, Japan, China, Australia: USPO.

    • Bufler, Michael (12.05.2021). Biomimetic collagen-hydroxyapatite composite material No. AU2018201667B2. Australia: IP Australia.

    • Bufler, Michael (15.04.2021). Biomimetic collagen-hydroxyapatite composite material No. JP2021052620A. Japan: Japan Patent Office.

    • Bufler, Michael (31.03.2021). Biphasic calcium phosphate/hydroxyapatite (CAP/HAP) bone substitute material No. AU2019298596B2. Australia: IP Australia.

    • Bufler, Michael (30.03.2021). Collagen matrix or granulate blend of bone substitute material No. 10960107. Unites States: USPTO.

    • Bufler, Michael (30.03.2021). COLLAGEN MATRIX OR GRANULATE BLEND OF BONE SUBSTITUTE MATERIAL No. 10960107B2. USA: USPTO.

    • Bufler, Michael (24.11.2020). Biphasic calcium phosphate/hydroxyapatite (CAP/HAP) bone substitute material No. BR112020013781-5. Brazil: Brazilian National Institute of Industrial Property.

    • Bufler, Michael (05.09.2020). Biomimetic collagen-hydroxyapatite composite material No. CN106850872B. China: China National Intellectual Property Administration.

    • Bufler, Michael (21.07.2020). Biomimetic collagen-hydroxyapatite composite material No. BR112018015688-0. Brazil: Brazilian National Institute of Industrial Property.

    • Bufler, Michael (28.05.2020). Biphasic calcium phosphate/hydroxyapatite (CAP/HAP) bone substitute material No. JP2020080703A. Japan: Japan Patent Office.

    • Bufler, Michael (13.05.2020). BONE SUBSTITUTE MATERIAL No. 3544643. DE, AT, BE, CZ, DK, FR, GB, HU, IE, IT, NO, PL, PT, ES, SE, CH, NL, TR: EPO.

    • Bufler, Michael (13.05.2020). BONE SUBSTITUTE MATERIAL No. 3544642. Europe: EPO.

    • Bufler, Michael (12.05.2020). BONE SUBSTITUTE MATERIAL No. 10646619. USA: USPTO.

    • Bufler, Michael (12.05.2020). Bone Substitute Material No. 10646615. United States: USPTO.

    • Bufler, Michael (04.02.2020). Biphasic calcium phosphate/hydroxyapatite (CAP/HAP) bone substitute material No. KR20200011012A. Korea: Korean Intellectual Property Office.

    • Bufler, Michael (16.11.2019). Biomimetic collagen-hydroxyapatite composite material No. 3021883. AT, BE, CH, CZ, DE, DK, ES, FR, GB, HU, IE, IT, NL, NO, PL, PT, SE, TR: EPO.

    • Bufler, Michael (17.10.2019). Biomimetic collagen-hydroxyapatite composite material No. KR1020190080076A. Korea: Korean Intellectual Property Office.

    • Bufler, Michael (25.09.2019). Bone Substitute Material No. 20200016293. United States: USPTO.

    • Bufler, Michael (11.07.2019). Bone Substitute Material No. 20190209737. United States: USPTO.

    • Bufler, Michael (09.07.2019). Hydrophilic phosphate group containing dehydrated partially purified bone replacement material No. BR112015002121-2. Brazil: Brazilian National Institute of Industrial Property.

    • Bufler, Michael (03.10.2018). Biphasic calcium phosphate/hydroxyapatite (CAP/HAP) bone substitute material No. CN106630181B. China: China National Intellectual Property Administration.

    • Bufler, Michael (24.07.2018). Biomimetic collagen-hydroxyapatite composite material No. US10029028B2. USA: USPTO.

    • Bufler, Michael (07.03.2018). Collagen Matrix or Granulate Blend of Bone Substitute Material No. EP3108997A1. Valid in all EPO member states: European Patent Office (EPO).

    • Bufler, Michael (22.03.2017). Biphasic calcium phosphate/hydroxyapatite (CAP/HAP) bone substitute material No. EP2796634B1. Valid in all EPO member states: European Patent Office (EPO).

    • Bufler, Michael (15.03.2017). Hydrophilic phosphate group containing dehydrated partially purified bone replacement material No. ZL201380040358.0. China: China National Intellectual Property Administration.

    • Bufler, Michael (15.03.2017). Hydrophilic phosphate group containing dehydrated partially purified bone replacement material No. ZL201380040358.0. China: CNIPA.

    • Bufler, Michael (14.12.2016). Biomimetic Collagen-Hydroxyapatite Composite Material No. EP2922651B1. Valid in all EPO member states: European Patent Office (EPO).

    • Bufler, Michael (29.04.2016). Hydrophilic phosphate group containing dehydrated partially purified bone replacement material No. 10-1619033. Korea: Korean Intellectual Property Office.

    • Bufler, Michael (21.10.2015). Hydrophilic phosphate group containing dehydrated partially purified bone replacement material No. 2879726. All countries covered by the EPO: EPO.

    • Bufler, Michael (21.10.2015). Hydrophilic phosphate group containing dehydrated partially purified bone replacement material No. 2879726. AT, BE, CH, DE, DK, ES, FR, GB, IT, NL, PL, PT, SE: EPO.

    • Bufler, Michael (30.06.2015). Bone Substitute Material No. 9066995. United States: United States Patent and Trademark Office (USPTO).

    • Bufler, Michael (11.02.2015). Bone substitute material No. 2654816. AT, BE, CH, CZ, DE, DK, ES, FR, GB, IE, IT, NL, PL, PT, SE: EPO.

Achievements - Patent

  • Bufler, Michael (30.06.2025). Bone substitute material No. 9066995. USA: USPTO.
  • Bufler, Michael (02.05.2023). COLLAGEN MATRIX OR GRANULATE BLEND OF BONE SUBSTITUTE MATERIAL No. ZL202080041436.9. China: CNIPA.
  • Bufler, Michael (23.03.2023). BONE SUBSTITUTE MATERIAL No. 7249376. Japan: JPO.
  • Bufler, Michael (28.12.2022). COLLAGEN MATRIX OR GRANULATE BLEND OF BONE SUBSTITUTE MATERIAL No. 3946488. DE, CH, ES, FR, GB, IT, NL: EPO.
  • Bufler, Michael (16.06.2022). COLLAGEN MATRIX OR GRANULATE BLEND OF BONE SUBSTITUTE MATERIAL No. 11357891. USA: USPTO.
  • Bufler, Michael (07.06.2022). BONE SUBSTITUTE MATERIAL No. 11351287. USA: USPTO.
  • Bufler, Michael (27.01.2022). Method for treating subjects suffering from chronic ulcers No. 20220023498. All Europen countries covered by the EPO, USA, Japan, China, Australia: USPO.
  • Bufler, Michael (12.05.2021). Biomimetic collagen-hydroxyapatite composite material No. AU2018201667B2. Australia: IP Australia.
  • Bufler, Michael (15.04.2021). Biomimetic collagen-hydroxyapatite composite material No. JP2021052620A. Japan: Japan Patent Office.
  • Bufler, Michael (31.03.2021). Biphasic calcium phosphate/hydroxyapatite (CAP/HAP) bone substitute material No. AU2019298596B2. Australia: IP Australia.
  • Bufler, Michael (30.03.2021). Collagen matrix or granulate blend of bone substitute material No. 10960107. Unites States: USPTO.
  • Bufler, Michael (30.03.2021). COLLAGEN MATRIX OR GRANULATE BLEND OF BONE SUBSTITUTE MATERIAL No. 10960107B2. USA: USPTO.
  • Bufler, Michael (24.11.2020). Biphasic calcium phosphate/hydroxyapatite (CAP/HAP) bone substitute material No. BR112020013781-5. Brazil: Brazilian National Institute of Industrial Property.
  • Bufler, Michael (05.09.2020). Biomimetic collagen-hydroxyapatite composite material No. CN106850872B. China: China National Intellectual Property Administration.
  • Bufler, Michael (21.07.2020). Biomimetic collagen-hydroxyapatite composite material No. BR112018015688-0. Brazil: Brazilian National Institute of Industrial Property.
  • Bufler, Michael (28.05.2020). Biphasic calcium phosphate/hydroxyapatite (CAP/HAP) bone substitute material No. JP2020080703A. Japan: Japan Patent Office.
  • Bufler, Michael (13.05.2020). BONE SUBSTITUTE MATERIAL No. 3544643. DE, AT, BE, CZ, DK, FR, GB, HU, IE, IT, NO, PL, PT, ES, SE, CH, NL, TR: EPO.
  • Bufler, Michael (13.05.2020). BONE SUBSTITUTE MATERIAL No. 3544642. Europe: EPO.
  • Bufler, Michael (12.05.2020). BONE SUBSTITUTE MATERIAL No. 10646619. USA: USPTO.
  • Bufler, Michael (12.05.2020). Bone Substitute Material No. 10646615. United States: USPTO.
  • Bufler, Michael (04.02.2020). Biphasic calcium phosphate/hydroxyapatite (CAP/HAP) bone substitute material No. KR20200011012A. Korea: Korean Intellectual Property Office.
  • Bufler, Michael (16.11.2019). Biomimetic collagen-hydroxyapatite composite material No. 3021883. AT, BE, CH, CZ, DE, DK, ES, FR, GB, HU, IE, IT, NL, NO, PL, PT, SE, TR: EPO.
  • Bufler, Michael (17.10.2019). Biomimetic collagen-hydroxyapatite composite material No. KR1020190080076A. Korea: Korean Intellectual Property Office.
  • Bufler, Michael (25.09.2019). Bone Substitute Material No. 20200016293. United States: USPTO.
  • Bufler, Michael (11.07.2019). Bone Substitute Material No. 20190209737. United States: USPTO.
  • Bufler, Michael (09.07.2019). Hydrophilic phosphate group containing dehydrated partially purified bone replacement material No. BR112015002121-2. Brazil: Brazilian National Institute of Industrial Property.
  • Bufler, Michael (03.10.2018). Biphasic calcium phosphate/hydroxyapatite (CAP/HAP) bone substitute material No. CN106630181B. China: China National Intellectual Property Administration.
  • Bufler, Michael (24.07.2018). Biomimetic collagen-hydroxyapatite composite material No. US10029028B2. USA: USPTO.
  • Bufler, Michael (07.03.2018). Collagen Matrix or Granulate Blend of Bone Substitute Material No. EP3108997A1. Valid in all EPO member states: European Patent Office (EPO).
  • Bufler, Michael (22.03.2017). Biphasic calcium phosphate/hydroxyapatite (CAP/HAP) bone substitute material No. EP2796634B1. Valid in all EPO member states: European Patent Office (EPO).
  • Bufler, Michael (15.03.2017). Hydrophilic phosphate group containing dehydrated partially purified bone replacement material No. ZL201380040358.0. China: China National Intellectual Property Administration.
  • Bufler, Michael (15.03.2017). Hydrophilic phosphate group containing dehydrated partially purified bone replacement material No. ZL201380040358.0. China: CNIPA.
  • Bufler, Michael (14.12.2016). Biomimetic Collagen-Hydroxyapatite Composite Material No. EP2922651B1. Valid in all EPO member states: European Patent Office (EPO).
  • Bufler, Michael (29.04.2016). Hydrophilic phosphate group containing dehydrated partially purified bone replacement material No. 10-1619033. Korea: Korean Intellectual Property Office.
  • Bufler, Michael (21.10.2015). Hydrophilic phosphate group containing dehydrated partially purified bone replacement material No. 2879726. All countries covered by the EPO: EPO.
  • Bufler, Michael (21.10.2015). Hydrophilic phosphate group containing dehydrated partially purified bone replacement material No. 2879726. AT, BE, CH, DE, DK, ES, FR, GB, IT, NL, PL, PT, SE: EPO.
  • Bufler, Michael (30.06.2015). Bone Substitute Material No. 9066995. United States: United States Patent and Trademark Office (USPTO).
  • Bufler, Michael (11.02.2015). Bone substitute material No. 2654816. AT, BE, CH, CZ, DE, DK, ES, FR, GB, IE, IT, NL, PL, PT, SE: EPO.

Achievements - Commissions, memberships and external activities

  • Bufler, Michael. Vorstandsmitglied des Industriesektors "Medical Manufacturing". (15.01.2025-2028). Swissmem, Industriesektor "Medical Manufacturing".
Biomimetic Architectures
Biofunctional Coatings
Material Science of Implantable Medical Devices